sirolimus

Sirolimus, Everolimus and Rapamycin is medication given to cancer patients and those who have been through an organ transplant.
It prevents your body from rejecting the new organ.

But it also inhibits mTOR and extent life.

Yet, the side effects are so severe it should not be used unless needed.

https://www.ncbi.nlm.nih.gov/pubmed/27208895

https://rapamycintherapy.com/